| World Cruiserweight Champions | Cumulative | |||||||||||
| Nat. | Date | Champion | Defeated | Result | W | Days | Years | Notes | W | Days | Years | Rank |
| USA | 3/31/1980 | Marvin Camel | Mate Parlov | W-15 | 1 | 239 | 0.65 | |||||
| PRI | 11/25/1980 | Carlos De Leon | Marvin Camel | W-15 | 1 | 579 | 1.59 | |||||
| USA | 6/27/1982 | ST Gordon | Carlos DeLeon | KO-2 | 2 | 385 | 1.05 | |||||
| PRI | 7/17/1983 | Carlos De Leon | ST Gordon | W-12 | 4 | 690 | 1.89 | |||||
| USA | 6/6/1985 | Alfonso Ratliff | Carlos DeLeon | W-12 | 1 | 107 | 0.29 | |||||
| USA | 9/21/1985 | Bernard Benton | Alfonso Ratliff | W-12 | 1 | 182 | 0.50 | |||||
| PRI | 3/22/1986 | Carlos De Leon | Bernard Benton | W-12 | 4 | 749 | 2.05 | |||||
| USA | 4/9/1988 | Evander Holyfield | Carlos DeLeon | KO-8 | 1 | 98 | 0.27 | |||||
| 7/16/1988 | Vacant | 305 | 0.84 | |||||||||
| PRI | 5/17/1989 | Carlos De Leon | Sammy Reeson | KO-9 | 2 | 436 | 1.19 | 11 | 2454 | 6.72 | 1 | |
| ITA | 7/27/1990 | Massimiliano Duran | Carlos DeLeon | DQ-11 | 2 | 134 | 0.37 | |||||
| FRA | 12/8/1990 | Anaclet Wamba | Massimiliano Duran | KO-11 | 8 | 1483 | 4.06 | 2 | ||||
| 12/30/1994 | Vacant | 207 | 0.57 | |||||||||
| ARG | 7/25/1995 | Marcelo Dominguez | Akim Tafer | KO-9 | 6 | 942 | 2.58 | 5 | ||||
| CUB | 2/21/1998 | Juan Carlos Gomez | Marcelo Dominguez | W-12 | 11 | 1459 | 4.00 | 3 | ||||
| 2/19/2002 | Vacant | 788 | 2.16 | |||||||||
| USA | 4/26/2003 | James Toney | Vassiliy Jirov | W-12 | 1 | 161 | 0.44 | |||||
| 10/4/2003 | Vacant | 196 | 0.54 | |||||||||
| GUY | 4/17/2004 | Wayne Braithwaite | Louis Azille | W-12 | 1 | 350 | 0.96 | |||||
| FRA | 4/2/2005 | Jean Marc Mormeck | Wayne Braithwaite | W-12 | 1 | 280 | 0.77 | |||||
| JAM | 1/7/2006 | O'Neil Bell | Jean Marc Mormeck | KO-10 | 1 | 434 | 1.19 | |||||
| FRA | 3/17/2007 | Jean Marc Mormeck | O'Neil Bell | W-12 | 1 | 238 | 0.65 | 2 | 518 | 1.42 | ||
| ENG | 11/10/2007 | David Haye | Jean Marc Mormeck | KO-7 | 2 | 184 | 0.50 | |||||
| 5/12/2008 | Vacant | 213 | 0.58 | |||||||||
| POL | 12/11/2008 | Tomasz Adamek | Steve Cunningham | W-12 | 3 | 317 | 0.87 | |||||
| 10/24/2009 | Vacant | 707 | 1.94 | |||||||||
| CUB | 10/1/2011 | Yoan Pablo Hernandez | Steve Cunningham | W-12 | 5 | 1457 | 3.99 | 4 | ||||
| 9/27/2015 | Vacant | 1028 | 2.82 | |||||||||
| UKR | 7/21/2018 | Oleksandr Usyk | Murat Gassiev | W-12 | 2 | 250 | 0.68 | |||||
| 3/28/2019 | Vacant | 548 | 1.50 | |||||||||
| LAT | 9/26/2020 | Mairis Briedis | Yuniel Dorticos | W-12 | 2 | 644 | 1.76 | |||||
| AUS | 7/2/2022 | Jai Opetaia | Mairis Briedis | W-12 | 4 | 686 | 1.88 | |||||
| 5/18/2024 | ||||||||||||